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\No IGF-1 Effects: Does not promote growth or exhibit pro-diabetic effects (Human Study)
If weight drops too fast, the body might break down bone faster than it can build it back up. Rapid weight loss can also temporarily increase circulating uric acid as fat stores break down, said Sonia Gibson, MD, an endocrinologist at Allara Health

Retatrutide is a next-generation weight loss injection developed by Eli Lilly (same manufacturer as Mounjaro), designed to target three separate hormone receptors in the body: the GLP-1 receptor, the GIP receptor, and the glucagon receptor

An update on global epidemiology in heart failure
