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The proportion of subjects with at least 50% decrease in AHI did not differ significantly between arms

Rather than suppressing caloric intake, they may enhance substrate utilization, preserve lean mass, and improve metabolic resiliencefeatures particularly relevant to aging populations, where sarcopenia, osteoporosis, and insulin resistance frequently coexist

Clinical trials demonstrate reductions in alanine aminotransferase (ALT) and aspartate aminotransferase (AST)key markers of liver healthoften correlating with decreased hepatic fat accumulation

In addition, retatrutide treatment for 48 weeks resulted in substantial reductions in body weight in individuals with a BMI 27 kg/m 2 [149]

This includes a 60-minute initial consultation, 2 lab draw appointments, 3 follow-ups and a program completion appointment