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Tirzepatide (TZP), a dual agonist of glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, has recently been introduced in Italy for the treatment of obesity
Tirzepatide reduced airway inflammation and neutrophil aggregation in obese asthmatic mice by inhibiting the Notch signaling pathway, which in turn decreased the differentiation of Th17 cells
