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Paradoxical emboli originate from the right side or systemic venous circulation, and pass from right to left through an atrial septal defect, patent foramen ovale, or pulmonary arteriovenous malformation

This work was supported by National Institutes of Health Grants DK123252 (P.M.T.), Cox Research Institute and internal funds from the University of Pennsylvania (P.M.T.) Data availability Data will be made available on request

One potential solution might lie at the Pennington Biomedical Research Center, where Dr

ACS Chem Neurosci

Consistent with the ability of GLP-1R agonists to decrease homeostatic and hedonic food intake (45, 46)