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A study published in the Journal of the American Medical Association (JAMA) found that people taking semaglutide drugs like Wegovy were twice as likely to develop NAION, a condition that causes permanent vision loss

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Signs of dehydration including reduced urine output, dark concentrated urine, dizziness on standing, dry mouth, and increased thirst should prompt urgent medical review, especially in vulnerable populations

GI side effects like diarrhea and constipation are most common during dose increases