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Lancet 370 , 12191229 (2007)

Regulation of Ca(V)2 calcium channels by G protein coupled receptors

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For others who dont have diabetes, it can be used for upwards of two years

Additionally, islets isolated from individuals with type 2 diabetes exhibit decreased DPP-4 activity in order to preserve GLP-1 secretion in culture, further implicating a functional role of endogenous islet GLP-1 in diabetes [29]