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These vitamin A metabolites, retinol and all-trans-retinal, not only function as potent RTAs (95) but also generate NADH through the ALDH1A3-catalyzed reaction, providing the reducing power necessary for the FSP1-CoQ10 system (63), In this way, they serve as important metabolic supplements to the canonical FSP1-CoQ10 antioxidant pathway

GCPR, G-coupled protein receptor

None of this means the concern is imaginary

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It is not suitable for those with a personal or familial history of medullary thyroid cancer, or multiple endocrine neoplasia syndrome type 2