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Patient compliance and maximal efficacy of GLP-1 therapeutics are limited by side effects including nausea and emesis

Compounded medications may differ from FDA-approved drugs in formulation, manufacturing controls, sterility testing, labeling, post-market surveillance, and required risk-management programs

Exendin-4 (E4), a long-acting GLP-1RA, has demonstrated neuroprotective effects in early experimental DR [49, 50]

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Non-insulin drugs may be continued, but SU discontinuation is preferred because of the increased risk of hypoglycemia.1214 Before prandial insulin is started, the basal glucose goal should have been achieved