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Bone biomarker for the clinical assessment of osteoporosis: Recent developments and future perspectives

Boxed warning: in rodent studies these medications caused thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)

10.1111/dom.14765 43 KnopF

DW is a 67-year-old woman with a history of coronary artery disease and prior percutaneous coronary intervention in 2019 with a drug-eluting stent to the proximal left anterior descending artery

There is accumulating evidence for numerous additional mechanisms of action separate from SGLT2 inhibition that appear to underlie the ability of gliflozins to produce additional effects associated with favorable outcomes, such as in the reduction of mortality and CV events in patients with heart failure