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GLP-1RA drugs effective to treat obesity could account for 3%4% of medical and Rx spend [73]

By elucidating the metabolic effects of allulose in a well-established animal model of T2D and obesity, this study seeks to contribute to the growing body of literature supporting the use of allulose as a safe and effective dietary intervention for managing these conditions

It has been estimated by studies with 1 H-magnetic resonance spectroscopy that decreasing bodyweight by 10% via diet combined with physical activity can induce a reduction in hepatic TG concentration up to nearly 60% in overweight individuals (3)

In general, the higher the BMI, the harder it is to take off weight and keep it off

These strategies compared to currently available drug medications such as thiazolidinediones, sulphonylureas, and insulin, have the potential to treat diabetes without causing side effects of hypoglycemia and weight gain