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Some patients on the pill will lose more than the average

Although GLP-1R has been detected in certain cases of thyroid and prostate cancer, its expression appears inconsistent and may lack functional relevance

The SURMOUNT trials for tirzepatide showed average losses of up to 22.5% of body weight figures that were previously only achievable with bariatric surgery

Because this was an observational study in a specific clinical population, randomized clinical trials are needed before GLP-1 medications can be recommended for treating addiction. However, the team believes their results are promising and plan to continue studying GLP-1s effect on substance abuse

doi: 10.1016/j.yhbeh.2019.104640 243 GejlMGjeddeAEgefjordLMollerAHansenSBVangKet al