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Employing alternative enzymes such as Glu-C and chymotrypsin enables targeted cleavage in regions otherwise inaccessible to trypsin

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The MOTS-c + NAD+ stack at Perfect B restores both the signaling mechanism (MOTS-c) and the energy substrate (NAD+), producing more consistent improvements in metabolic energy, body composition, and insulin sensitivity than either protocol alone

This mitochondrial protection is especially critical in PD, where neuronal loss is driven by apoptotic processes [78]