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doi: 10.1111/sms.12450 112 WolfsdorfJIAllgroveJCraigMEEdgeJGlaserNJainVet al

Subcutaneous injection is the most common route of administration for Semaglutide

This was further supported by the finding that the additional enhancement of secretion by glutamine was maintained in the presence of 10 mol/l forskolin plus 10 mol/l IBMX (4.5-fold increase by 10 mmol/l glutamine vs 3.0-fold increase by 25 mmol/l glucose

These studies reveal that the pharmacology profile of tirzepatide is not only determined by the peptide sequence, but also the location and composition of the acyl side chain