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The endogenous GLP-1 system in the regulation of energy homeostasis The endogenous GLP-1 system is densely populated in areas that control energy homeostasis placing it in the neuroanatomical position to regulate food intake and body weight

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Exendin-4 then proved safe and effective in humans, leading to the 2005 US Food and Drug Administration (FDA) approval of exenatide, under the name Byetta

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The FAERS database was queried from 2005 Q2 to 2023 Q2