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Whereas corticosteroids and biologics affect immune system and may expose patients to adverse effects such as infections, GLPs do not act directly as immunosuppressants and may become first-line therapy in the treatment of IBD

Neural crest tissue migrates into the tube and forms two major collections of endocardial cushion tissue
Mol Metab, 30:72-130

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Patients should be educated on the need for long-term treatment with these medications, as well as the cost and adverse reactions