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Typically, phentermine and metformin arent prescribed together unless an individuals obesity is related to diabetes, polycystic ovarian syndrome (PCOS), or metabolic syndrome

They break down if exposed to heat or digestive enzymes, so they need refrigerated storage and subcutaneous injection
and/or recurrent gingivostomatitis (rare), depending on clinical judgement

Discuss all current medications with your provider before starting

They want a jumpstart
