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Can J Diabetes (2014) 38(5):36471.10.1016/j.jcjd.2014.05.001 67 KrasnerNMIdoYRudermanNBCacicedoJM

Prior Medication History: VA clinical guidelines require that you try and fail, or have a medical contraindication to, first-line generic diabetes medications (such as metformin) or other specific formulary alternatives before stepping up to a GLP-1

These medicines regulate blood sugar levels and support weight loss by reducing hunger and slowing digestion, leading to lower food intake

FDA approval ensures that the medications have been thoroughly tested, but ongoing research continues to monitor their long-term effects

Secretory progenitors differentiate into EEC progenitors through the expression of the neurogenin 3 (Ngn3) transcription factor