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GLP-1 receptor agonists are drugs that bind to GLP-1 receptors, mimicking the effects of GLP-1

The GLP-1/Notch signaling within the distal niche maintains the mitotic cell fate of germline SPCs ( glp-1(gf) mutant animals with excessive GLP-1 activity have slightly enhanced proliferation of germline SPCs at the permissive temperature, and produce tumorous germlines at the restrictive temperature (Wang et al., 2012)

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Los datos que respaldan la inyeccin de 2,0 mg de semaglutida para la diabetes tipo 2 se derivaron del ensayo SUSTAIN FORTE, en el que los pacientes tratados con la dosis ms alta del agonista GLP-1 lograron reducciones estadsticamente significativas y superiores en la hemoglobina A1c (HbA1c) en la semana 40 en comparacin con los pacientes que recibieron 1,0 mg de semaglutida