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Description
The additional properties of inhibition of glucagon secretion and inhibition of caloric intake accelerated the development of GLP-1 receptor agonists for usage in type 2 diabetes management [86]

Her PMHx includes type 2 diabetes mellitus (T2DM) for which she takes metformin XR 1g BD, gliclazide 60mg daily, and her recently commenced weekly semaglutide injection

This was followed by the observation that GIP could also stimulate insulin secretion in animals and humans, and thus, it was later renamed as glucose-dependent insulinotropic polypeptide, while retaining the same acronym (Dupre et al., 1973

Gastrointestinal side effects were common at 3-month follow-up, but the incidence decreased as the patients sustained the therapy
Unlike Zepbound and Mounjaro, it is not FDA approved and is unlikely to be covered by insurance
