semaglutide compulsive behavior as a promising new treatment for alcohol use disorder Ozempic is hailed as a

Supporting information Acknowledgements The authors appreciate Animal Resources Facility and Winship Cancer Tissue and Pathology at Emory University School of Medicine (Winship Cancer InstituteNIH 5P30CA138292)

Many studies emphasize its capacity to upregulate endogenous antioxidant defenses and suppress oxidative stress in inflammatory and precancerous settings (Jakubczyk et al., 2020)

GLP-1 receptor signaling also involves genetic variation

At lower BMIs: Clinical trial evidence is limited Metabolic risk is reduced Appetite suppression may become excessive PGDs are deliberately conservative and evidence-led

Methotrexate, by contrast, suppresses immune cell proliferation and reduces inflammatory moleculesa mechanism used for rheumatoid arthritis, lupus, and other autoimmune conditions