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, GLP-1 SCI (Nutrients) 14
Nature 528, 262266
Taken together, these studies demonstrate the relative inability of GLP-1R to undergo desensitization, i.e., to uncouple from G s proteins and cAMP production, neither in vivo (in animal models and humans), nor in cultured cells expressing physiological levels of native GLP-1R in vitro (Figure 1 and Figure 2)
4.Kelly T, Yang W, Chen C-S, Reynolds K, He J
Strokovna priporoila za zdravljenje debelosti z zdravili (Professional Guidelines for the Pharmacological Treatment of Obesity)
