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FAQs Is Ozempic insulin

The trials missed their primary endpoint

These findings are consistent with our work in which beta-cell GLP-1R signaling was found to contribute to improved islet function after VSG (39), which was associated with a VSG-induced beta-cell GLP-1R-dependent increase in islet GLP-1 production in mice (40)

[DOI] [PMC free article] [PubMed] [Google Scholar] 242.Whyte M.B., et al

Primary Endpoint: Weight Loss at 72 Weeks The results were striking and clinically significant: Zepbound Group: Participants achieved an average weight reduction of 20.2% at 72 weeks Wegovy Group: Participants achieved an average weight reduction of 13.7% at 72 weeks Relative Difference: Zepbound provided 47% greater relative weight loss compared to Wegovy To put this in practical terms: A patient weighing 250 pounds could expect to lose approximately 50 pounds with Zepbound versus 34 pounds with Wegovy over the same timeframe