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Description
Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity
Treatment with 30 g/kg AC3174, an exenatide analog, administered via an osmotic pump for 28 days in Lep ob mice on a high trans -fat diet significantly reduced liver weight, hepatic lipid accumulation, and plasma alanine transaminase levels in comparison with pair-fed, weight-matched controls (30)
van Schaik J, Begijn DGA, van Iersel L, et al
With medication discontinuation, symptoms typically resolve within days to weeks
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