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In extreme situations, losses to vision can occur within hours of onset, and while this effect can worsen in the following weeks, once the optic nerve's swelling goes down after a month or two, there can be some visual improvement

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This duration helps distinguish normal fluctuations from potential treatment resistance or underlying medical issues requiring investigation

Available as: Last cited 6 Sept 2023 Urva S, OFarrell L, Du Y, Loh MT, Hemmingway A, Qu H, Alsina-Fernandez J, Haupt A, Milicevic Z, Coskun T (2023) The novel GIP, GLP-1 and glucagon receptor agonist retatrutide delays gastric emptying