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They serve as an adjunct tool to support continued appetite control and metabolic health in the long term

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Diabetes Obes Metab 19, 14461453 (2017)

Artificial sweeteners induce glucose intolerance by altering the gut microbiota
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It should be noted that it may take 3 months to titrate subcutaneous semaglutide to a 1-mg dose, and therefore the maximum glycemic benefit of that agent may not be evident for up to 6 months after the switch
