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1 Introduction Glucagon-like peptide-1 (GLP-1) is a gut peptide hormone that functions as an incretin that plays a key role in controlling satiety and various other physiological functions

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No longer viewed as merely a passive energy storage site, adipose tissue functions as a highly active, complex endocrine and immunologic organ

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As such, the full impact of IcoSema on glycaemic management is greater than that illustrated by HbA 1c alone

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Changed side effect profile

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These often decrease over time as the body adjusts to the medication

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