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The oral DPP4 inhibitors sitagliptin (marketed as Januvia ) and vildagliptin (marketed as Glavus ) have been shown to reduce the overall percentage of HbA 1c by about 0.6-0.7%

3 Because postprandial hyperglycemia affects A1C to a greater degree than fasting hyperglycemia, the closer a patient is to the A1C goal, GLP-1 receptor agonists provide a viable treatment option to target postprandial glucose excursions due to their glucose-dependent effects on insulin secretion

For stimulants and opioids, we currently have only preclinical rodent studies, but these show good effects

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