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In order to gain a better understanding of the role of GLP-1 agonists in ALS and their potential for clinical translation we conducted in vivo pharmacology studies with liraglutide following established guidelines for preclinical testing 11

consequently, the AMPK-activating antidiabetic agents may likely affect the regulation of the immune system (12)

The samples were acquired at 25 C according to literature procedure using a Biacore X100 instrument equipped with a CM5 sensor chip (GE Healthcare Biosciences) 48

Patient safety and follow-up: Patients should be educated about deficiency symptoms and encouraged to report concerns promptly
