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[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Obesity and overweight
10.1056/NEJMoa2108269 [DOI] [PubMed] [Google Scholar] 40
By week 4, most patients report clearer appetite control and the beginning of sustained weight reduction as their body adapts to the medication
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GLP-1 receptor agonists such as semaglutide established that pharmacologic activation of gut hormone pathways could produce double-digit percentage weight loss in many patients
