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Furthermore, the evidence base for the mechanisms possibly involved in the mood-regulating properties of these medications appear more tentative and would benefit from a more in-depth assessment
doi: 10.2337/dc12-2454 51 WildingJPHBatterhamRLCalannaSDaviesMVan GaalLFLingvayIet al

In contrast, the pharmacological nanomolar concentrations of GLP-1RAs predominantly activate the cAMP/PKA pathway, potentially explaining their broader therapeutic effects [122]
