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The reckoning for investors arrived on August 5, 2025, when a dramatic lowering of the full-year guidance triggered a massive sell-off

For Canadians exploring surgical and non-surgical weight management pathways, this related guide provides helpful context: The Ultimate Guide to Weight Loss Surgery in Canada Understanding all available options helps Canadians make informed decisions with their care teams

[DOI] [PubMed] [Google Scholar] 68.Ryan D, Acosta A

Cellular damage and declining repair mechanisms contribute to systemic decline, some of which may be modifiable through targeted interventions [1]

Furthermore, the patient's AUDIT score improved from a high-risk 27 to a 7, representing a clinically significant 20-point reduction