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Tirzepatide works by targeting both GLP-1 and GIP receptors, resulting in greater weight loss and better glucose lowering than medications that target GLP-1 alone, said Isaacs

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In addition to pain relief, semaglutide improved physical function, measured by the SF-36 Health Survey, with an average increase of 12 points, nearly doubling the improvement seen with placebo

The table below summarizes the studies on orlistat (Table 4)
[DOI] [PubMed] [Google Scholar] 31.Tirzepatide for heart failure with preserved ejection fraction and obesity
