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Incretin therapies mimic or enhance the action of gut hormones primarily glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) to

GLP-1 medications may help address menopause-related weight gain by regulating appetite and metabolism, but individual response depends on hormonal status, metabolic biomarkers, and genetic predispositions

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These newer agents may further assist in the effective pharmacological management of T2D through the provision of patient-centered care that acknowledges multimorbidity and is respectful of and responsive to individual patient preferences and barriers

Zoloft can potentially cause weight gain (or even weight loss), but not everyone who takes sertraline will experience this side effect.