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Description
The STEP 1 trial showed that semaglutide 2.4mg produced average weight loss of approximately 15% of body weight after 68 weeks

Interestingly, chronic chemo-genetic stimulation of POA LepR-expressing neurons decreases both food intake and energy expenditure, and results in body weight loss, indicating that the reduced food intake surpasses the decreased energy expenditure [28]

Even the best possible response to medication is unlikely to produce enough weight loss, he says
Vit-B6 Reduces nausea, a frequent side effect of GLP-1 medications, improving tolerance and adherence to therapy

Ozempic butt is the loss of volume, sagging skin and flat appearance of the buttocks resulting from rapid fat and muscle loss during GLP-1 medication treatment like Ozempic or Wegovy