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Patients taking Zepbound and other GLP-1s are suffering from gut paralysis, vision loss, and other side effects, which can be life-threatening or permanent

The side effect profile is dose-dependent, predictable, and in most cases manageable with proper preparation

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Further, experimental data suggest that the pro-survival action of GLP-1RAs may also be mediated by the Akt-dependent stimulation of the mTORC1/S6K1 pathway, the activation of which is dependent upon the IGF-1R, as observed in rodent islet cells (44)

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