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Further randomised controlled and pragmatic trials are needed to define their potential benefits/harms, mechanisms of action and where GLP1RAs might fit into existing treatment pathways for uncontrolled asthma

Research from the Cardiovascular Outcomes Progression Trial showed that GLP-1 receptor agonists improve liver fat content, HbA1c, and blood pressureoutcomes that correlate directly with visceral fat reduction rather than total weight loss alone

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