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The Food and Drug Administration claims a European pharmaceutical company failed to properly report side effects tied to its popular weight loss drugs

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Conditions such as atopic dermatitis, gastroesophageal reflux disease (GERD), urinary incontinence, whose association with obesity is well documented, 54 were not included

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The injection site should be free of bruising, tenderness, injury, scars, or stretch marks

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In 2023, Juan P Frias and colleagues, in The Lancet, published the first phase two clinical trial of orforglipron, which investigated the use of a small-molecule oral GLP-1R agonist called orforglipron in type 2 diabetes, which can be taken at any time of the day without restrictions on food and water intake (Frias et al., 2023)

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