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In another phase 3 analysis, retatrutide at the highest dose reached up to 28.7% weight loss, making it the most potent weight loss medication ever tested in large-scale clinical trials

GLP-1, or glucagon-like peptide-1, is a hormone that plays a significant role in regulating appetite and glucose metabolism

Additionally, it showed further improvement in lipid parameters in patients already on secondary prevention

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1 Participants carrying one copy of the variant lost an average of 1.7 pounds more over a median of eight months of treatment compared to non-carriers, while those carrying two copies lost approximately 3.3 pounds more