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Before combining these compounds, schedule a telehealth consultation with a provider familiar with both GLP-1 therapy and botanical compounds

The SURMOUNT-4 trial showed that people who continued tirzepatide after their initial plateau lost an additional 5.5 percent of body weight, while those switched to placebo regained 14 percent

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But it does add an important nuance: for patients taking GLP-1 medications to manage diabetes (rather than purely for weight loss), there may be a net benefit to gum health IF the other side effects (dry mouth, vomiting, nutritional gaps) are actively managed

The brain samples were embedded in the 4%UltraPure low melting point agarose (Invitrogen) in PBS on the ice