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Apart from pancreatic islets, GIP and GLP-1 receptors have been identified in several other organs, including the intestine, heart, brain, and kidney

These medications do not directly target cellular energy production or mitochondrial function

R., Loureiro-Campos E., et al

All other authors declare that there are no relationships or activities that might bias, or be perceived to bias, their contribution to this manuscript

Inflammation, mitochondrial impairment, oxidative stress, and insulin resistance may all contribute to disease progression
