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Importantly the inferred sequence of the platypus GLP-1 peptide (pGLP-1) differs in 11 of the 30 amino acids (37%) compared to human GLP-1 (hGLP-1, Fig

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Other documented side effects include injection site reactions (for subcutaneous formulations), fatigue, and headache
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A combination of PDO threads, biostimulators like Sculptra and Radiesse, and microneedling with radiofrequency can address skin laxity