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The most common causes of bleeding during a bowel movement are actually rectal: Hemorrhoids: Swollen blood vessels in the lower rectum or anus that can rupture under pressure
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Near-maximal, approximately 75% reductions were associated with approximately 20% reductions in body weight

The STEP program, which included over 4,500 participants, demonstrated that patients on semaglutide achieved average weight reductions of 14-15% over 68 weeks, compared to less than 3% in the placebo group
