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Comorbidities included hypertensive diseases, ischemic heart disease, heart failure, cerebrovascular diseases, diseases of arteries, arterioles, and capillaries, disorders of lipoprotein metabolism and other dyslipidemias, obesity, chronic lower respiratory diseases, vitamin D deficiency, neoplasms, chronic kidney disease, depressive episodes, major depressive disorder, recurrent, noninfective enteritis and colitis, liver diseases, infections of the skin and subcutaneous tissue, viral hepatitis, rheumatoid arthritis with rheumatoid factor, other rheumatoid arthritis, gout, osteoarthritis, systemic lupus erythematosus, and ankylosing spondylitis

Clinical trials show average weight loss of 15-22% over 68 weeks on semaglutide alone, with some patients reaching 25%+ loss

A lower fat diet may be better tolerated for people experiencing gut-related side effects like bloating, heart burn or diarrhoea

Long-Term Outcomes of Sleeve Gastrectomy Versus Gastric Bypass

As an alternative, the Food and Drug Administration has allowed pharmacies to create similar, but not officially approved, substitutes called compounded medications