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To determine the direct effect of exendin 939 on the time that mice spent licking their hind paws in the CAP-induced spontaneous pain model, intraplantar administration of exendin 939 (doses of 5 and 10 g) was followed by intraplantar administration of CAP (1.6 g)

Orforglipron doesnt have any restrictions in terms of food intake or the time you take it, says Julio Rosenstock, MD, the lead author of the new study, the director of Velocity Clinical Research, and a professor at the University of Texas Southwestern Medical Center in Dallas

And the answer is yes, frequently they can be and are prescribed together

Pratter, the U.S

J Pharmacol Exp Ther 316 : 440447