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Rapid lowering of blood glucose after prolonged periods of poor control can temporarily worsen diabetic retinopathya condition sometimes called "early worsening"

In this context, through studies on microbiota in the state of health and disease, new probiotics based on specific commensals with different anti-inflammatory effects, such as Akkermansia or Fecalibacterium, are being developed [70]

You can do all of that and end up with nothing, Raufman said

However, these latter effects are currently only observed in animal studies

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