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doi: 10.1056/NEJMoa1911303 63 PackerMAnkerSDButlerJFilippatosGPocockSJCarsonPet al

A 20-pound loss is more realistic after 4+ months on weight loss medication

Cohort studies represented 74.4% of GLP-1 studies, 60.0% of dual GIP/GLP-1 studies, and 41.7% of non-GLP-1 studies

The role of DMH GLP-1R neurons can be likened to stepping on a vehicles brake in response to a traffic signala learned anticipatory mechanism that prepares for meal termination independently of gut-derived feedback

95% CI, 0.74-1.39) were also assessed
