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25 In the early 1990s, despite John Engs team identifying a potential diabetes treatment in exendin-4, it initially lacked attention and funding for development
Effect of the once-daily human GLP-1 analogue liraglutide on appetite, energy intake, energy expenditure and gastric emptying in type 2 diabetes
465 Impaired GLP-1 secretion or reduced GLP-1R expression may result in aberrantly heightened sympathetic excitation
Wang J, Markesbery WR, Lovell MA
