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The Clinical Trial Data Weight Loss Results The clinical data for orforglipron is compelling

Glucagon like peptide-1 (GLP-1) is the natural ligand of GLP-1R

When phase 3 data pushed retatrutide to 28.7% at the highest dose, the gap widened further
Rafael Mayoral Monibas Ph.D.s Post Latest review of the Tirzepatide dual receptor agonist GLP-1/GIP, summarizing five clinical trials in type 2-diabetic subjects.
BMJ Open 14 , e083550 (2024)
