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Direct demonstration of brain insulin resistance in Alzheimers and Parkinsons disease dementia and its alleviation with incretin receptor agonists

Mller cell gliosis, marked by an increase in glial fibrillary acidic protein (GFAP), can cause excitotoxicity-induced cell death of RGCs [92]
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[80] were able to show how both topical and systemic liraglutide administration prevented retinal degeneration in db/db mice

And this is part of why appetite regulation becomes harder
