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Patients who stopped taking GLP-1 weight-loss medications regained weight four times as fast as those using alternative methods.

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Pausing semaglutide therapy requires careful planning and medical guidance

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By pairing a rapid "research flywheel" with large-scale genomic data, 23andMe Research Institute scientists identified GLP1R and GIPR variants associated with some of the variability in individual response to GLP-1 drugs, helping bridge the gap between patient experiences and precision medicine.